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Best-in-class precision ocular ASO therapeutics driven by human genetics

Our Mission

We leverage human genetics and best-in-class antisense oligonucleotide (ASO) technology to deliver life-changing, precision ocular ASO medicines.

Our focus on differentiated ASO technology, powered by Alloy Therapeutics’ Genetic Medicines platform and novel AntiClastic™ ASO format, paves the way for a unique and rapid path to meaningful ocular solutions for patients.

Our Approach

Our next-generation AntiClastic ASO medicines

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Precise Design

Uses established building blocks that make clinical and market-validated ASOs.

icon Improved Potency
Improved Potency

Leverages proprietary structures to improve potency and promote the delivery of antisense to target RNA, and optimizes engagement of RNaseH for precise excision.

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Better Medicines

Minimizes off-target interactions with unintended RNA targets , mitigates the inflammatory response—potentially improving the therapeutic index.

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Our Approach

Treating severe blinding diseases

Aldebaran utilizes ocular disease genetics to identify targets for well-defined patient populations with broad therapeutic potential. We are passionate about finding solutions for:

  • Inherited retinal disease
  • Age-related macular degeneration
  • glaucoma
Our Science

Ocular Disease Genetics

We are advancing a diversified portfolio of precision ocular AntiClastic ASOs for patients with severe blinding diseases. We are using human iPSC and in vivo models to de-risk and accelerate therapeutics to the clinic.

Meet our team
Hundreds of genes and Millions of patients: Common Hundreds of Genes and Thousands of Patients: Rare
Our Team

We have assembled a world-class group of company builders, scientists, and leaders at the forefront of ocular research and development and ASO therapeutics.

Carlos Loya
Carlos Loya, PhD

Founder,  CEO, Board Director

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Sudhir Agrawal
Sudhir Agarwal, PhD

Co-Founder, SAB Member

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Andrew Peterson
Andrew Peterson, PhD

Co-Founder, SAB Member

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Vinod Vathipadiekal
Vinod Vathipadiekal, PhD

Board Director, Alloy Head of Genetic Medicines

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Eric Anderson
Errik Anderson

CEO, Founder of Alloy Therapeutics

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Chris Pacheco
Chris Pacheco, PhD

Board Director

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Our Investors
82VS - The venture studio of Alloy Therapeutics

82VS, the venture studio of Alloy Therapeutics, helps efficiently launch new multi-asset startup companies by leveraging the capabilities of the Alloy ecosystem at large.

Learn more about 82VS
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Let’s make better ocular medicines, together.

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